Dietary Supplement Fact Sheet :

Yohimbine (Pausinystalia yohimbe), Also known as: Yohimbe, Quebrachine.

Historical Perspective:
 Yohimbine is the major alkaloid found in the bark of the Corynanthe yohimbe tree indigenous to West Africa. Yohimbine is a monoamine oxidase inhibitor that stimulates an increase in norepinephrine release. The bark is used primarily as an aphrodisiac in Africa.

Common Uses:
Used in tablet, capsule, and tincture form for increased serum testosterone levels, muscle growth and strength, weight loss, fatigue and sexual function. (Yohimbe has been studied as a way to reduce fatigue in AIDS patients and as a libido enhancer.)

Potential Side Effects:
Yohimbine ingestion (4mg to 20 mg) has been associated with side effects including nervousness, insomnia, anxiety, urinary frequency, dizziness, tremors, headache, tachycardia, hypotension, hypertension, nausea and vomiting, brochospasm and lupuslike syndrome.

Food-Drug-Supplement Interactions:
Drugs such as phenothiazines enhance yohimbine toxicity. Nasal decongestants or diet products containing phenylpropaanolamine should be avoided to prevent a hypertensive crisis.

Contraindications:
Yohimbine is contraindicated in individuals with high or low blood pressure, bipolar disorder, existing liver and kidney disease, or patients who are pregnant or breast feeding or on tricyclic antidepressants.

Research Data on Safety and Efficacy:
There are no long-term studies of yohimbine safety. Many studies have been conducted on yohimbine and sexual function but there is insuffi cient proof of effi cacy.

All About Yohimbe Bark
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History of Yohimbe Bark
What Does Yohimbe Do
Yohimbine Alkaloids of Rauwolfia serpentina
How Does Yohimbine Work Explained in Detail
Dietary Supplement Fact Sheet
Yohimbine Drug Nutrient/Herb Interactions
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