Yohimbine Alkaloids of Rauwolfia serpentina :

Rauwolfia serpentinaRauwolfia serpentina is a tree in Africa Central which is extracted from the yohimbine alkaloid substance, which is a drug with capacity to dilate blood vessels, and part of the family of sympatholytic (alpha blockers), that is to say substances that inhibit the action of the sympathetic nervous system. Sympatholytics inhibit the functioning of the nervous system said vegetative in its part sympathetic.

The automatic functions of our body are managed by two systems: the sympathetic and parasympathetic. Adrenaline is a hormone produced by the adrenal glands located above each kidney. It has a leading role in the functioning of sympathetic nervous system said, whose action is mainly excitatory.

The yohimbine acts by binding on adrenergic receptors (specifically alpha adrenergic) cells of the body, thus preventing the release of adrenaline. These vasodilatory effects expressed mainly in peripheral circulation blood in the arteries of the skin, intestines, the urinary and genital, especially in the corpus cavernosum of the penis is the reason why it is proposed as an aphrodisiac.Alkaloids

Yohimbine has a share in the corpora cavernosa containing many blood vessels filling with blood during erection. Thus, yohimbine is indicated for the treatment of male impotence because it allows the opening of the vessels and improvement of filling in this part of the penis, , and thus a better erection.

It is also used in the syndrome orthostatic hypotension, which results in a drop in pressure pressure when an individual moves suddenly from a lying position standing position.

Against-the indications of yohimbine are essentially severe renal insufficiency and hepatic.

Adverse events occurring at doses high are
Insomnies, dizziness, headaches, nervousness, nausea, vomiting, diarrhea, tremors.

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