Yohimbine Drug Nutrient/Herb Interactions :
Yohimbe : a-adrenoceptor blocking agents3 - Increases toxicity of yohimbine |
(Pausinystalia yohimbe) - Bark : e.g. Phenoxybenazamine, phentolamine3 |
| Amobarbital | Interact |
| Antidepressants | Interact |
| Atropine | Interact |
| Beta blockers e.g. Propranolol, penbutolol, metrprolol | Protects against yohimbine toxicity (mice) |
| Central a-adrenergic agonists e.g. Guanabenz, a-methylnorepinephrine | Reverses hypotensive effects |
| Clonidine | Reverses hypotensive effects |
| Hypotensive drugs | Potentiates |
| MAOIs | Potentiates; |
| Naloxone | Affects synergistically enhances |
| Phenothiazines e.g. Chlorpromazine, promazine | Increases toxicity of yohimbine |
| Reserpine | Interact |
| Sedatives | Increases effect of drug |
| SSRIs | Increases stimulation |
| Sympathomimetics e.g. Epinephrine, ephedrine, amphetamine, cocaine | Increases toxicity of yohimbine |
| Thiozanthenes e.g. Chlorprotixene | Increases toxicity of yohimbine |
| Tricyclic anti-depressants e.g. Clomipramine, imipramine, amitriptyline | Combination of herb and drug may cause hypertension Lower doses of yohimbine may have favorable effect in orthostatic hypotension induced by tricyclic anti-depressants |
| Tyramine containing foods | Increases blood pressure |
Remedies: Depression, Male impotence |